Reference

Relevant publications on VULNOFAST® products:

• Photodynamic antibacterial and antibiofilm activity of RLP068/Cl against Staphylococcus aureus and Pseudomonas aeruginosa forming biofilms on prosthetic material.
  Vassena C., Fenu S., Giuliani F. Fantetti L., Roncucci G., Simonutti G., Romanò C.L., De Francesco R., Drago L. International Journal of Antimicrobial Agents 2014; 44(1): 47-55.

• Photodynamic topical antimicrobial therapy for infected foot ulcers in patients with diabetes: a randomized, double-blind, placebo-controlled study--the D.A.N.T.E (Diabetic ulcer Antimicrobial New Topical treatment Evaluation) study.
  Mannucci E., Genovese S., Monami M., i Navalesi G., Dotta F., Anichini R., Romagnoli F., Gensini G. Acta Diabetologica 2014; 51(3): 435-40.

• Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion.
  Vecchio D., Dai T., Huang L., Fantetti L., Roncucci G., Hamblin M.R. Journal of Biophotonics, 2012; 1–11.

• Effectiveness of antimicrobial photodynamic therapy with a single treatment of RLP068⁄Cl in an experimental model of Staphylococcus aureus wound infection.
  Simonetti O., Cirioni O., Orlando F., Alongi C., Lucarini G., Silvestri C., A. Zizzi A., L. Fantetti L., Roncucci G., Giacometti A., Offidani A., Provinciali M. British Journal of Dermatology 2011; 164: 987–995

• In vitro resistance selection studies of RLP068/Cl, a new Zn(II)phthalocyanine suitable for antimicrobial photodynamic therapy.
  Giuliani F., Martinelli M., Cocchi A., Arbia D. Fantetti L., Roncucci G. Antimicrobial Agents Chemotherapy 2010; 54(2):637-42

• Phthalocyanines as photodynamic agents for the inactivation of microbial pathogens.
  Dei D., Chiti G., De Filippis M.P., Fantetti L., Giuliani F., Giuntini F., Soncin M., Jori G. and Roncucci G. Journal of Porphyrins and Phthalocyanines 2006; 10: 147-159

Additional selected literature

• Contribution of photodynamic therapy in wound healing: a systematic review.
  Nesi-Reis V, Lera-Nonose DSSL, Oyama J, Silva-Lalucci MPP, Demarchi IG, Aristides SMA, Teixeira JJV, Silveira TGV, Lonardoni MVC. Photodiagnosis and Photodynamic Therapy, 2018; 21:294-305

• Photoantimicrobials - are we afraid of the light?
  Wainwright M, Maisch T, Nonell S, Plaetzer K, Almeida A, Tegos GP, Hamblin MR. Lancet Infect Dis, 2017;17(2):e49-e55.

• New photosensitizers for photodynamic therapy.
  Abrahamse H, Hamblin MR. Biochem J. 2016; 473:347-364.

• Photodynamic therapy as a new treatment modality for inflammatory and infectious conditions
  Reinhard A, Sandborn WJ, Melhem H, Bolotine L, Chamaillard M, Peyrin-Biroulet L. Expert Rev Clin Immunol, 2015; 11(5):637-57.

• A clinical trial testing the efficacy of PDT in preventing amputation in diabetic patients.
  Tardivo J.P., Adami F., Correa J.A., Pinhal M.A.S., Baptista M.S. Photodiagnosis and Photodynamic Therapy, 2014; 11:342-350.

• In defence of 'dye therapy.
  Wainwright M. . Int J Antimicrob Agents. 2014; 44(1):26-9.